Genomic Analyses
We study how DNA sequence composition and non-B DNA structures shape genomic instability, evolution, and cancer.
Learn moreDecoding cancer genomics through computational biology
The Georgakopoulos-Soares Laboratory is dedicated to advancing our understanding of the genomic and molecular mechanisms that drive cancer evolution. By integrating large-scale sequencing data, computational modeling, and AI-driven analytics, the lab develops novel approaches to dissect the mutational signatures that shape cancer genomes and influence tumor progression.
Our research combines bioinformatics, systems biology, and data visualization to explore how genomic instability, replication stress, and DNA repair pathways interact across different cancer types. Through this multi-layered perspective, we aim to reveal hidden patterns within the genome that can inform the development of more precise diagnostic and therapeutic strategies.
Beyond fundamental research, the lab is committed to building open-source tools and resources for the scientific community. By fostering collaboration, transparency, and data accessibility, we strive to accelerate discoveries in cancer genomics and empower researchers worldwide to translate genomic insights into clinical impact.

We study how DNA sequence composition and non-B DNA structures shape genomic instability, evolution, and cancer.
Learn moreDeveloping algorithms that surface actionable insights from complex data.
Learn moreWe develop algorithms for diagnosing, monitoring, and treating human diseases.
Learn more…, I Mouratidis, I Georgakopoulos-Soares - arXiv preprint arXiv …, 2025 - arxiv.org
I Mouratidis, I Georgakopoulos-Soares
…, A Karatzikos, I Georgakopoulos-Soares - arXiv preprint arXiv …, 2025 - arxiv.org
I Georgakopoulos-Soares
…, P Ziros, I Habeos, I Georgakopoulos-Soares - Journal of the American …, 2025 - jaad.org
P Ziros, I Habeos, I Georgakopoulos-Soares

Principal Investigator

Research Scientist

Research Scientist

Research Fellow

Electrical and Computer Engineer

PhD Student

Software and Machine Learning EngineerSoftware Engineering, Artificial Intelligence, Bioinformatics

PhD Student

Research Scientist
Researcher

Bioinformatician

PhD Student
Electrical and Computer Engineer

Rotation Student

Research Scientist

Rotation Student